The MOGAT1 Antibody (PAC010543) is a crucial tool for researchers studying the MOGAT1 gene, which encodes an enzyme involved in the synthesis of triglycerides. This polyclonal antibody, produced in rabbits, is highly specific for human samples and is validated for use in various applications, including Western blotting.MOGAT1 plays a key role in lipid metabolism, making it a target of interest in metabolic disorders, obesity, and other related conditions. By detecting and analyzing MOGAT1 protein expression in different cell types, researchers can gain valuable insights into lipid synthesis and storage mechanisms, paving the way for potential therapeutic interventions.
Understanding the function and regulation of MOGAT1 is essential for unraveling the complexities of lipid metabolism and its implications for human health. The MOGAT1 Antibody provides a reliable tool for investigating the role of this enzyme in physiological processes and disease states, offering new avenues for exploration in the fields of biochemistry and metabolic research.
MOGAT1: Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Probably not involved in absorption of dietary fat in the small intestine. Belongs to the diacylglycerol acyltransferase family.Protein type: Endoplasmic reticulum; Membrane protein, multi-pass; Transferase; Membrane protein, integral; EC 2.3.1.22Chromosomal Location of Human Ortholog: 2q36.1Cellular Component: endoplasmic reticulum membraneMolecular Function: 2-acylglycerol O-acyltransferase activityBiological Process: triacylglycerol biosynthetic process
UniProt Protein Details:
NCBI Summary:
Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerols, the precursor of physiologically important lipids such as triacylglycerol and phospholipids (Yen et al., 2002 [PubMed 12077311]).[supplied by OMIM, Mar 2008]
