The Moesin Polyclonal Antibody (CAB2178) is a powerful tool for research involving Moesin, a protein involved in cell structure and signaling pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot and immunohistochemistry applications. By specifically binding to Moesin, this antibody allows for the detection and analysis of Moesin expression in a variety of cell types, making it an essential tool for studies in cell biology and cancer research.Moesin plays a crucial role in cell structure and function, particularly in processes such as cell motility, adhesion, and signal transduction.
Dysregulation of Moesin expression has been associated with various diseases, including cancer, inflammatory disorders, and neurological conditions. Understanding the role of Moesin in these diseases is essential for the development of targeted therapies and diagnostic tools.Overall, the Moesin Polyclonal Antibody (CAB2178) is a valuable resource for researchers interested in studying the functions and mechanisms of Moesin in health and disease. Its high specificity and sensitivity make it an ideal choice for investigating the role of Moesin in various cellular processes and pathological conditions.
Product Name:
Moesin Rabbit Polyclonal Antibody
SKU:
CAB2178
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human Moesin (NP_002435.1).
Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.
Purification Method:
Affinity purification
Gene ID:
4478
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Moesin antibody (CAB2178) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.