The MOCS2 Polyclonal Antibody (PACO10541) is a valuable tool for researchers studying the MOCS2 protein, which plays a crucial role in molybdenum cofactor biosynthesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the MOCS2 protein, this antibody enables the detection and analysis of MOCS2 in various cell types, making it an ideal choice for investigations in biochemistry and molecular biology.
MOCS2 is essential for the proper functioning of molybdenum cofactor-dependent enzymes, which are involved in critical cellular processes such as metabolism and detoxification. Dysregulation of MOCS2 has been linked to severe health conditions, including metabolic disorders and neurological diseases. Research into the role of MOCS2 is essential for understanding the mechanisms underlying these disorders and for developing targeted therapies to address them.
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
NCBI Summary:
Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits. [provided by RefSeq, Jul 2008]
