MOB1A/MOB1B Rabbit Polyclonal Antibody (CAB18246)
- SKU:
- CAB18246
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MOB1A/MOB1B Rabbit Polyclonal Antibody |
SKU: | CAB18246 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human MOB1A/MOB1B (NP_060691.2/NP_775739.1). |
Sequence: | TILK RLFR VYAH IYHQ HFDS VMQL QEEA HLNT SFKH FIFF VQEF NLID RREL APLQ ELIE KLGS KDR/ MSFL FGSR SSKT FKPK KNIP EGSH QYEL LKHA E |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | MOB1A/MOB1B |
Positive Sample: | K-562,Daudi,NIH/3T3,C6,C2C12 |
Cellular Localization: | cytoplasm, cytosol, extracellular exosome, nucleolus, nucleoplasm, nucleus |
Observed MW: | 24kDa |
The protein MOB1 is considered to be one of the core components of the mammalian Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. MOB1A and MOB1B, which have 95% sequence identity, play redundant biological roles and are both termed MOB1.
Purification Method: | Affinity purification |
Gene ID: | 55233/92597 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |