The MOB1A/MOB1B Polyclonal Antibody (CAB18246) is a valuable tool for researchers studying MOB1A and MOB1B proteins, which are key regulators of cell division and growth. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications.MOB1A and MOB1B are essential components of the Hippo signaling pathway, which controls organ size and tissue homeostasis. Dysregulation of this pathway has been implicated in various diseases, including cancer.
The MOB1A/MOB1B Polyclonal Antibody binds specifically to these proteins, enabling accurate detection and analysis in a variety of cell types.Research into MOB1A and MOB1B is vital for understanding their roles in cell proliferation, apoptosis, and tumor development. By targeting these proteins, researchers can uncover new therapeutic strategies for cancer treatment and other diseases related to cell growth and division. Unlock the potential of MOB1A and MOB1B research with the CAB18246 Polyclonal Antibody.
Product Name:
MOB1A/MOB1B Rabbit Polyclonal Antibody
SKU:
CAB18246
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human MOB1A/MOB1B (NP_060691.2/NP_775739.1).
The protein MOB1 is considered to be one of the core components of the mammalian Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. MOB1A and MOB1B, which have 95% sequence identity, play redundant biological roles and are both termed MOB1.
Purification Method:
Affinity purification
Gene ID:
55233/92597
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MOB1A/MOB1B Rabbit pAb (CAB18246) at 1:1500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
