null

MOB1A/B Monoclonal Antibody

SKU:
CAB23963
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
IF
€139 - €529
Frequently bought together:

Description

MOB1A/B Monoclonal Antibody (CAB23963)

The MOB1A/B Monoclonal Antibody is a specialized research tool designed for the detection and analysis of MOB1A and MOB1B proteins in various cell types. These proteins are key regulators of cell proliferation and cell cycle progression, making them important targets for study in cancer research and developmental biology.This monoclonal antibody, produced through hybridoma technology, offers high specificity and sensitivity in detecting MOB1A and MOB1B proteins in Western blot and immunofluorescence applications.

Its ability to bind specifically to these proteins allows for accurate quantification and visualization in experimental settings.Research utilizing the MOB1A/B Monoclonal Antibody can provide valuable insights into the mechanisms governing cell growth and division, as well as their dysregulation in diseases such as cancer. By understanding the roles of MOB1A and MOB1B in cellular processes, researchers can develop targeted therapies and interventions for managing these conditions effectively.

Product Name:MOB1A/B Monoclonal Antibody
Product Code:CAB23963
Reactivity:Human, Mouse, Rat
Applications:Western blotting, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC62859
Reactivity:Human, Mouse, Rat
Tested Applications:WB, IF/ICC, ELISA
Key Applications:Western blotting, Immunofluorescence
Recommended Dilution:WB 1:1000-1:5000, IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:K-562, Daudi, HuH-7(Low expression control), C6
Cellular Location:Cytoplasm, nucleus

The protein encoded by this gene is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MOB1A/B (NP_060691.2).
Sequence:MSFLF SSRSS KTFKP KKNIP EGSHQ YELLK HAEAT LGSGN LRQAV MLPEG EDLNE WIAVN TVDFF NQINM LYGTI TEFCT EASCP VMSAG PRYEY HWADG
Synonyms:MOB1, MATS1, Mob4B, C2orf6, MOBK1B, MABKL1B, MOBKL1B
Calculated MW:25kDa
Observed MW:25kDa

Related Products