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MND1 Antibody (PACO10533)

SKU:
PACO10533
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
$551
Frequently bought together:

Description

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MND1 Antibody (PACO10533)

The MND1 Monoclonal Antibody (PACO10533) is a valuable tool for research involving MND1, a protein essential for meiotic recombination and fertility in mammals. This antibody, generated using hybridoma technology, is highly specific to mouse MND1 and is validated for use in immunofluorescence and immunohistochemistry applications. It binds to the MND1 protein, allowing for precise detection and localization in various tissues and cell types, making it ideal for studies in reproductive biology and genetics.MND1, a meiosis-specific protein, is crucial for ensuring proper chromosome segregation and genetic diversity during gamete formation.

Its role in meiotic recombination makes it a key player in fertility and reproductive health. Research on MND1 is essential for understanding the molecular mechanisms underlying meiosis and for developing treatments for infertility and genetic disorders related to meiotic defects.Overall, the MND1 Monoclonal Antibody (PACO10533) offers researchers a reliable tool for investigating the functions and mechanisms of MND1 in meiosis, opening up new possibilities for advancing our understanding of reproductive biology and genetic diversity.

Antibody Name:MND1 Antibody (PACO10533)
Antibody SKU:PACO10533
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse
Immunogen:Human MND1
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:meiotic nuclear divisions 1 homolog (S. cerevisiae);MND1;GAJ ;
UniProt Protein Function:MND1: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks. Belongs to the MND1 family.
UniProt Protein Details:

Protein type:Unknown function

Chromosomal Location of Human Ortholog: 4q31.3

Cellular Component: nucleus

Molecular Function:DNA binding

Biological Process: meiotic cell cycle; DNA recombination

NCBI Summary:The product of the MND1 gene associates with HOP2 (MIM 608665) to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 (MIM 179617) and DMC1 (MIM 602721) (Chi et al., 2007 [PubMed 17639080]). Both the MND1 and HOP2 genes are indispensable for meiotic recombination.[supplied by OMIM, Mar 2008]
UniProt Code:Q9BWT6
NCBI GenInfo Identifier:74733462
NCBI Gene ID:84057
NCBI Accession:Q9BWT6.1
UniProt Secondary Accession:Q9BWT6,B2R5F9,
UniProt Related Accession:Q9BWT6
Molecular Weight:205
NCBI Full Name:Meiotic nuclear division protein 1 homolog
NCBI Synonym Full Names:meiotic nuclear divisions 1 homolog (S. cerevisiae)
NCBI Official Symbol:MND1  
NCBI Official Synonym Symbols:GAJ  
NCBI Protein Information:meiotic nuclear division protein 1 homolog; MND1; homolog of yeast MND1
UniProt Protein Name:Meiotic nuclear division protein 1 homolog
Protein Family:MND1-interacting protein
UniProt Gene Name:MND1  
UniProt Entry Name:MND1_HUMAN

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