The MNAT1 Polyclonal Antibody (CAB1918) is a valuable tool for researchers studying MNAT1, a crucial protein involved in cell cycle regulation. This antibody, generated in rabbits, shows high specificity and reactivity with human samples, making it ideal for Western blot applications. By binding to the MNAT1 protein, this antibody allows for accurate detection and analysis in various cell types, enabling in-depth studies in molecular biology and cancer research.MNAT1, also known as CDK activating kinase, plays a critical role in activating cyclin-dependent kinases (CDKs) essential for cell division.
Dysregulation of MNAT1 is linked to abnormal cell proliferation, making it a promising target for cancer therapy and drug development. Understanding the function of MNAT1 is key to unraveling its role in tumorigenesis and identifying potential therapeutic strategies to combat cancer growth.Overall, the MNAT1 Polyclonal Antibody (CAB1918) is a valuable tool for researchers investigating the role of MNAT1 in cell cycle regulation and cancer progression, providing insights into potential therapeutic targets for cancer treatment.
Product Name:
MNAT1 Rabbit Polyclonal Antibody
SKU:
CAB1918
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human MNAT1 (NP_002422.1).
WB,1:500 - 1:1000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
MAT1; TFB3; CAP35; RNF66; MNAT1
Positive Sample:
A-431
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
36kDa
Observed MW:
36kDa
The protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4331
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from A-431 cells, using MNAT1 Rabbit pAb (CAB1918) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
