[KO Validated] MMP9 Rabbit Polyclonal Antibody (CAB2095)
- SKU:
- CAB2095
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] MMP9 Rabbit Polyclonal Antibody |
SKU: | CAB2095 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 538-707 of human MMP9 (NP_004985.2). |
Sequence: | KYWR FSEG RGSR PQGP FLIA DKWP ALPR KLDS VFEE RLSK KLFF FSGR QVWV YTGA SVLG PRRL DKLG LGAD VAQV TGAL RSGR GKML LFSG RRLW RFDV KAQM VDPR SASE VDRM FPGV PLDT HDVF QYRE KAYF CQDR FYWR VSSR SELN QVDQ VGYV TYDI LQCP ED |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | GELB; CLG4B; MMP-9; MANDP2; MMP9 |
Positive Sample: | K-562,Mouse brain,Mouse spleen,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 78kDa |
Observed MW: | 100kDa/84kDa |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Purification Method: | Affinity purification |
Gene ID: | 4318 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |