The MMP9 Polyclonal Antibody (CAB11391) is a specialized tool designed for researchers studying matrix metalloproteinase 9 (MMP9), an enzyme involved in extracellular matrix degradation and tissue remodeling. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards MMP9 in human samples, making it a reliable choice for Western blot analyses.MMP9 is a key player in various physiological and pathological processes, such as wound healing, angiogenesis, and cancer invasion. By targeting MMP9, researchers can gain insights into its role in disease progression and explore its potential as a therapeutic target.
This antibody enables precise detection and quantification of MMP9 levels in different cell types, paving the way for advancements in cancer research, regenerative medicine, and drug development.Understanding the intricate regulation of MMP9 activity is crucial for unraveling its impact on disease pathogenesis and identifying novel treatment strategies. By utilizing the MMP9 Polyclonal Antibody, researchers can delve deeper into the functions of MMP9 and expand our knowledge of its implications in health and disease.
Product Name:
MMP9 Rabbit Polyclonal Antibody
SKU:
CAB11391
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 401-500 of human MMP9 (NP_004985.2).
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Purification Method:
Affinity purification
Gene ID:
4318
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human stomach using MMP9 Rabbit pAb (CAB11391) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
