MMP8 Rabbit Polyclonal Antibody (CAB1963)
- SKU:
- CAB1963
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MMP8 Rabbit Polyclonal Antibody |
SKU: | CAB1963 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 101-467 of human MMP8 (NP_002415.1). |
Sequence: | LTPG NPKW ERTN LTYR IRNY TPQL SEAE VERA IKDA FELW SVAS PLIF TRIS QGEA DINI AFYQ RDHG DNSP FDGP NGIL AHAF QPGQ GIGG DAHF DAEE TWTN TSAN YNLF LVAA HEFG HSLG LAHS SDPG ALMY PNYA FRET SNYS LPQD DIDG IQAI YGLS SNPI QPTG PSTP KPCD PSLT FDAI TTLR GEIL FFKD RYFW RRHP QLQR VEMN FISL FWPS LPTG IQAA YEDF DRDL IFLF KGNQ YWAL SGYD ILQG YPKD ISNY GFPS SVQA IDAA VFYR SKTY FFVN DQFW RYDN QRQF MEPG YPKS ISGA FPGI ESKV DAVF QQEH FFHV FSGP RYYA FDLI AQRV TRVA RGNK WLNC RYG |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | HNC; CLG1; MMP-8; PMNL-CL; MMP8 |
Positive Sample: | HepG2,A-549,Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasmic granule, Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 53kDa |
Observed MW: | 60kDa |
This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 4317 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |