MMP27 Antibody (PACO18242)
- SKU:
- PACO18242
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
MMP27 Antibody (PACO18242)
The MMP27 Monoclonal Antibody (PAC018242) is a crucial tool for researchers studying matrix metalloproteinase 27 (MMP27), a key enzyme involved in extracellular matrix remodeling and tissue degradation. This highly specific antibody, developed using cutting-edge technology, is recommended for use in immunohistochemistry and Western blotting applications.MMP27 is a member of the matrix metalloproteinase family, which has been implicated in a variety of physiological and pathological processes, including wound healing, tissue development, and cancer progression.
By targeting MMP27 with this monoclonal antibody, researchers can gain valuable insights into its expression patterns and functional role in various cellular contexts.With its high specificity and sensitivity, the MMP27 Monoclonal Antibody offers researchers a reliable tool for investigating the role of MMP27 in disease processes, particularly in cancer metastasis and tissue remodeling. Its versatility and consistency make it a valuable asset for studies aimed at understanding the complex mechanisms underlying these pathological conditions.
| Antibody Name: | MMP27 Antibody (PACO18242) |
| Antibody SKU: | PACO18242 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human MMP27 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18242(MMP27 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 10%SDS-PAGE, Lysate: 80 μg, Lane: Mouse brain tissue, Primary antibody: PACO18242(MMP27 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO18242(MMP27 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. |
| Synonyms: | Matrix metallopeptidase 27 |
| UniProt Protein Function: | MMP27: Matrix metalloproteinases degrade protein components of the extracellular matrix such as fibronectin, laminin, gelatins and/or collagens. Belongs to the peptidase M10A family. |
| UniProt Protein Details: | Protein type:EC 3.4.24.-; Secreted; Secreted, signal peptide; Protease Chromosomal Location of Human Ortholog: 11q24 Cellular Component: extracellular matrix Molecular Function:zinc ion binding; metalloendopeptidase activity; calcium ion binding Biological Process: collagen catabolic process; proteolysis |
| NCBI Summary: | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9H306 |
| NCBI GenInfo Identifier: | 296437372 |
| NCBI Gene ID: | 64066 |
| NCBI Accession: | Q9H306.2 |
| UniProt Secondary Accession: | Q9H306,Q6UWK6, |
| UniProt Related Accession: | Q9H306 |
| Molecular Weight: | 513 |
| NCBI Full Name: | Matrix metalloproteinase-27 |
| NCBI Synonym Full Names: | matrix metallopeptidase 27 |
| NCBI Official Symbol: | MMP27Â Â |
| NCBI Official Synonym Symbols: | MMP-27Â Â |
| NCBI Protein Information: | matrix metalloproteinase-27; matrix metalloprotease 27; matrix metalloproteinase 27 |
| UniProt Protein Name: | Matrix metalloproteinase-27 |
| Protein Family: | Matrix metalloproteinase |
| UniProt Gene Name: | MMP27Â Â |
| UniProt Entry Name: | MMP27_HUMAN |
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