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MMP23A Antibody (PACO05558)

SKU:
PACO05558
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
$323
Frequently bought together:

Description

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MMP23A Antibody (PACO05558)

The MMP23A Antibody (PACO05558) is a valuable tool for researchers studying matrix metalloproteinase 23A, an enzyme involved in extracellular matrix remodeling and tissue homeostasis. This polyclonal antibody, generated through immunization of rabbits, is highly specific for human samples and is validated for use in Western blot applications. By binding to the MMP23A protein, this antibody allows for the accurate detection and analysis of MMP23A levels in various cell types, making it an essential component for studies in cancer biology, tissue development, and wound healing.Matrix metalloproteinases play a crucial role in various physiological and pathological processes, including tissue remodeling, angiogenesis, and cancer progression.

MMP23A, in particular, has been implicated in promoting tumor invasion and metastasis, making it a promising target for anti-cancer therapies. Understanding the regulation and function of MMP23A is essential for developing strategies to modulate its activity and potentially inhibit cancer cell migration and invasion. In conclusion, the MMP23A Antibody (PACO05558) is a reliable tool for researchers investigating the role of MMP23A in health and disease. Its specificity, sensitivity, and versatility make it an indispensable resource for advancing our understanding of matrix metalloproteinase biology and developing targeted therapies for cancer and other conditions.

Antibody Name:MMP23A Antibody (PACO05558)
Antibody SKU:PACO05558
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:ELISA:1:10000, WB:1:500-1:2000
Species Reactivity:Human, Mouse, Rat
Immunogen:Synthesized peptide derived from the C-terminal region of human MMP-23.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:MMP23A; MMP21; MMP23B; MMP21; MMP22; Matrix metalloproteinase-23; MMP-23; Femalysin; MIFR-1; Matrix metalloproteinase-21; MMP-21; Matrix metalloproteinase-22; MMP-22
UniProt Protein Function:MMP23B: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum. Belongs to the peptidase M10A family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral; EC 3.4.24.-; Protease

Chromosomal Location of Human Ortholog: 1p36.3

Cellular Component: proteinaceous extracellular matrix; endoplasmic reticulum membrane; integral to membrane; intracellular

Molecular Function:zinc ion binding; metallopeptidase activity; metalloendopeptidase activity

Biological Process: proteolysis; reproduction

NCBI Summary:This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region. [provided by RefSeq, Jul 2008]
UniProt Code:O75900
NCBI GenInfo Identifier:117949605
NCBI Gene ID:8510
NCBI Accession:O75900.2
UniProt Secondary Accession:O75900,O75894, O75895, Q5QPQ8, Q76P96, Q7LDM6, Q7LDM7 Q9UBR9, Q9UJK8, A2AGN0, A2AGN1,
UniProt Related Accession:O75900
Molecular Weight:46,305 Da
NCBI Full Name:Matrix metalloproteinase-23
NCBI Synonym Full Names:matrix metallopeptidase 23B
NCBI Official Symbol:MMP23B  
NCBI Official Synonym Symbols:MIFR; MMP22; MIFR-1; MMP23A  
NCBI Protein Information:matrix metalloproteinase-23; MMP-21; MMP-22; MMP-23; femalysin; matrix metalloproteinase 22; matrix metalloproteinase 23B; matrix metalloproteinase in the female reproductive tract; matrix metalloproteinase-21; matrix metalloproteinase-22
UniProt Protein Name:Matrix metalloproteinase-23
UniProt Synonym Protein Names:Femalysin; MIFR-1; Matrix metalloproteinase-21; MMP-21; Matrix metalloproteinase-22; MMP-22
UniProt Gene Name:MMP23A  
UniProt Entry Name:MMP23_HUMAN

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