MMP20 Rabbit Polyclonal Antibody (CAB9788)
- SKU:
- CAB9788
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | MMP20 Rabbit Polyclonal Antibody |
SKU: | CAB9788 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 108-310 of human MMP20 (NP_004762.2). |
Sequence: | YRLF PGEP KWKK NTLT YRIS KYTP SMSS VEVD KAVE MALQ AWSS AVPL SFVR INSG EADI MISF ENGD HGDS YPFD GPRG TLAH AFAP GEGL GGDT HFDN AEKW TMGT NGFN LFTV AAHE FGHA LGLA HSTD PSAL MYPT YKYK NPYG FHLP KDDV KGIQ ALYG PRKV FLGK PTLP HAPH HKPS IPDL CDSS SSFD AVTM LGK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | AI2A2; MMP-20; MMP20 |
Positive Sample: | U-87MG,mouse brain,rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 54kDa |
Observed MW: | 54kDa |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3.
Purification Method: | Affinity purification |
Gene ID: | 9313 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |