The MMP20 Polyclonal Antibody (CAB9788) is a valuable tool for researchers studying matrix metalloproteinase 20 (MMP20), an enzyme involved in the breakdown of extracellular matrix proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting MMP20 in human samples, making it an excellent choice for Western blot applications.MMP20 plays a crucial role in various physiological processes, including tissue remodeling, wound healing, and bone development. Dysregulation of MMP20 activity has been implicated in various diseases, such as cancer, arthritis, and cardiovascular disorders.
By using the MMP20 Polyclonal Antibody, researchers can effectively study MMP20 expression and function in different cell types, providing valuable insights into its role in health and disease.With its ability to detect MMP20 with precision, the MMP20 Polyclonal Antibody is a powerful tool for advancing research in fields such as oncology, musculoskeletal disorders, and cardiovascular health. By understanding the mechanisms underlying MMP20 activity, scientists can potentially identify new therapeutic targets for the treatment of MMP20-related diseases.
Product Name:
MMP20 Rabbit Polyclonal Antibody
SKU:
CAB9788
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 108-310 of human MMP20 (NP_004762.2).
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3.
Purification Method:
Affinity purification
Gene ID:
9313
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MMP20 Rabbit pAb (CAB9788) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
