The MMP19 Polyclonal Antibody (CAB6657) is a crucial tool for researchers studying Matrix Metalloproteinase 19 (MMP19), an enzyme involved in tissue remodeling and cell migration. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications, allowing for accurate detection and analysis of MMP19 expression in various cell types.MMP19, a member of the matrix metalloproteinase family, is known for its role in extracellular matrix remodeling, particularly during processes like wound healing, angiogenesis, and tumor progression.
By targeting MMP19, researchers can gain valuable insights into the mechanisms underlying these physiological and pathological processes, making this antibody a valuable asset in studies related to cancer, tissue regeneration, and inflammation.Understanding the function and regulation of MMP19 is essential for developing targeted therapies aimed at modulating its activity for therapeutic benefit. With the MMP19 Polyclonal Antibody (CAB6657), researchers can delve deeper into the complexities of MMP19 biology, paving the way for innovative approaches in drug discovery and personalized medicine.
Product Name:
MMP19 Rabbit Polyclonal Antibody
SKU:
CAB6657
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 209-508 of human MMP19 (NP_002420.1).
This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene.
Purification Method:
Affinity purification
Gene ID:
4327
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse lung, using MMP19 antibody (CAB6657) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
