The MMP16 Polyclonal Antibody (CAB10409) is a valuable tool for researchers studying Matrix Metalloproteinase 16 (MMP16), a crucial enzyme involved in extracellular matrix remodeling and tissue homeostasis. This antibody, produced in rabbits, has high specificity and sensitivity for detecting MMP16 in human samples, making it ideal for use in various research applications such as Western blotting.MMP16 is known for its role in tissue remodeling processes, such as wound healing, cell migration, and angiogenesis. Dysregulation of MMP16 activity has been implicated in various diseases, including cancer, fibrosis, and inflammatory disorders.
By utilizing the MMP16 Polyclonal Antibody, researchers can investigate the expression and function of MMP16 in different cell types, providing insights into its involvement in disease pathogenesis and potential therapeutic targets.Overall, the MMP16 Polyclonal Antibody offers a reliable tool for studying MMP16 biology, offering valuable information for research in the fields of cancer biology, tissue remodeling, and therapeutic development.
Product Name:
MMP16 Rabbit Polyclonal Antibody
SKU:
CAB10409
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 290-565 of human MMP16 (NP_005932.2).
Cell membrane, Cell surface, Extracellular side, Secreted, Single-pass type I membrane protein, extracellular matrix, extracellular space.
Calculated MW:
70kDa
Observed MW:
70kDa
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.
Purification Method:
Affinity purification
Gene ID:
4325
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MMP16 Rabbit pAb (CAB10409) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
