MMP12 Rabbit Monoclonal Antibody (CAB3713)
- SKU:
- CAB3713
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MMP12 Rabbit Monoclonal Antibody |
SKU: | CAB3713 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 371-470 of human MMP12 (P39900). |
Sequence: | FGFP NFVK KIDA AVFN PRFY RTYF FVDN QYWR YDER RQMM DPGY PKLI TKNF QGIG PKID AVFY SKNK YYYF FQGS NQFE YDFL LQRI TKTL KSNS WFGC |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ME; HME; MME; MMP-12; MMP12 |
Positive Sample: | A-549,BxPC-3,Mouse lung,Mouse brain,Mouse spleen,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 54kDa |
Observed MW: | 45kDa/54kDa |
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11.
Purification Method: | Affinity purification |
Gene ID: | 4321 |
Clone Number: | ARC0280 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |