MMP11 Rabbit Monoclonal Antibody (CAB11088)
- SKU:
- CAB11088
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MMP11 Rabbit Monoclonal Antibody |
SKU: | CAB11088 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 389-488 of human MMP11 (P24347). |
Sequence: | AALV WGPE KNKI YFFR GRDY WRFH PSTR RVDS PVPR RATD WRGV PSEI DAAF QDAD GYAY FLRG RLYW KFDP VKVK ALEG FPRL VGPD FFGC AEPA NTFL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | ST3; SL-3; STMY3; MMP11 |
Positive Sample: | 293T,A549,MCF7,Mouse lung,Mouse testis,Mouse kidney,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, Extracellular matrix, Extracellular space |
Calculated MW: | 55kDa |
Observed MW: | 55kDa |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.
Purification Method: | Affinity purification |
Gene ID: | 4320 |
Clone Number: | ARC0523 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |