MMP1 Rabbit Polyclonal Antibody (CAB1191)
- SKU:
- CAB1191
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | MMP1 Rabbit Polyclonal Antibody |
SKU: | CAB1191 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human MMP1 (NP_002412.1). |
Sequence: | FPAT LETQ EQDV DLVQ KYLE KYYN LKND GRQV EKRR NSGP VVEK LKQM QEFF GLKV TGKP DAET LKVM KQPR CGVP DVAQ FVLT EGNP RWEQ THLT YRIE NYTP DLPR ADVD HAIE KAFQ LWSN VTPL TFTK VSEG QADI MISF VRGD HRDN SPFD GPGG NLAH AFQP GPGI GGDA HFDE DERW TNNF REYN LHRV AAHE LGHS LGLS HSTD IGAL MYPS YTFS GDVQ LAQD DIDG IQAI YGRS QNPV QPIG PQTP KACD S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CLG; CLGN; MMP1 |
Positive Sample: | SKOV3 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 54kDa |
Observed MW: | 55kDa |
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method: | Affinity purification |
Gene ID: | 4312 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |