The MMP1 Polyclonal Antibody (CAB1191) is a valuable tool for researchers studying matrix metalloproteinase 1 (MMP1), an enzyme that plays a key role in tissue remodeling and degradation. This antibody is raised in rabbits and is highly specific for human samples, making it an ideal choice for experiments involving MMP1 protein detection.MMP1 is involved in processes such as wound healing, tissue repair, and tumor invasion, highlighting its importance in various physiological and pathological conditions. By using the MMP1 Polyclonal Antibody, researchers can accurately detect and analyze MMP1 expression in cell lysates or tissue samples, providing insights into the enzyme's activity and potential implications in diseases like cancer and arthritis.
With its high specificity and sensitivity in Western blot applications, the MMP1 Polyclonal Antibody is a valuable tool for investigating the role of MMP1 in various biological processes. Researchers can utilize this antibody to advance their understanding of MMP1 function and explore its potential as a therapeutic target for diseases associated with abnormal tissue remodeling.
Product Name:
MMP1 Rabbit Polyclonal Antibody
SKU:
CAB1191
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human MMP1 (NP_002412.1).
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method:
Affinity purification
Gene ID:
4312
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of SKOV3 cells, using MMP1 antibody (CAB1191) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
