MMP1 Monoclonal Antibody (CAB22080)
- SKU:
- CAB22080
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | MMP1 Monoclonal Antibody |
SKU: | CAB22080 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 93-210 of human MMP1 (NP_002412.1). |
Sequence: | GVPD VAQF VLTE GNPR WEQT HLTY RIEN YTPD LPRA DVDH AIEK AFQL WSNV TPLT FTKV SEGQ ADIM ISFV RGDH RDNS PFDG PGGN LAHA FQPG PGIG GDAH FDED ERWT NNFR EY |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:2000 - 1:20000 |
Synonyms: | CLG; CLGN; MMP1 |
Positive Sample: | A-375, SK-OV-3, Mouse bone,Rat spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 54kDa |
Observed MW: | 62kDa |
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method: | Affinity purification |
Gene ID: | 4312 |
Clone Number: | ARC55239 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |