MMGT1 Antibody (PACO28290)
- SKU:
- PACO28290
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
MMGT1 Antibody (PACO28290)
The MMGT1 Monoclonal Antibody (PAC02890) is a valuable tool for researchers studying the MMGT1 protein, a key player in cellular processes related to metabolism and growth. This antibody, produced in a laboratory setting, is highly specific to human samples and is recommended for use in immunofluorescence and immunohistochemistry applications. By targeting the MMGT1 protein, researchers can gain insights into its function in various cell types, making it a versatile tool for studies in cell biology and disease mechanisms.
MMGT1, also known as a metabolic regulator, is essential for maintaining cellular homeostasis and controlling energy production. Its involvement in metabolic pathways and growth signaling pathways makes it a promising target for research on metabolic disorders, cancer, and other diseases with metabolic dysregulation. Understanding the role of MMGT1 can lead to the development of targeted therapies aimed at restoring normal cellular function in these conditions.
| Antibody Name: | MMGT1 Antibody (PACO28290) |
| Antibody SKU: | PACO28290 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Membrane magnesium transporter 1 protein (66-131AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: MMGT1 antibody at 12µg/ml Lane 1: Hela whole cell lysate Lane 2: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 15, 22 kDa Observed band size: 15 kDa . |
 | Immunofluorescence staining of HepG2 cells with PACO28290 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Mediates Mg2+ transport. |
| Synonyms: | Membrane magnesium transporter 1 (ER membrane protein complex subunit 5) (Transmembrane protein 32), MMGT1, EMC5 TMEM32 |
| UniProt Protein Function: | TMEM32: Mediates Mg(2+) transport. Belongs to the membrane magnesium transporter (TC 1.A.67) family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: Xq26.3Cellular Component: early endosome; Golgi apparatus; integral to membrane; membraneMolecular Function: magnesium ion transmembrane transporter activityBiological Process: magnesium ion transport |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8N4V1 |
| NCBI GenInfo Identifier: | 74751006 |
| NCBI Gene ID: | 93380 |
| NCBI Accession: | Q8N4V1.1 |
| UniProt Secondary Accession: | Q8N4V1,Q5JPP7, B2R625, B4DIY3, D3DWG7 |
| UniProt Related Accession: | Q8N4V1 |
| Molecular Weight: | 21,881 Da |
| NCBI Full Name: | Membrane magnesium transporter 1 |
| NCBI Synonym Full Names: | membrane magnesium transporter 1 |
| NCBI Official Symbol: | MMGT1Â Â |
| NCBI Official Synonym Symbols: | EMC5; TMEM32Â Â |
| NCBI Protein Information: | membrane magnesium transporter 1 |
| UniProt Protein Name: | Membrane magnesium transporter 1 |
| UniProt Synonym Protein Names: | ER membrane protein complex subunit 5; Transmembrane protein 32 |
| Protein Family: | Membrane magnesium transporter |
| UniProt Gene Name: | MMGT1Â Â |
| UniProt Entry Name: | MMGT1_HUMAN |
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