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MMADHC Rabbit Polyclonal Antibody (CAB15820)

SKU:
CAB15820
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:MMADHC Rabbit Polyclonal Antibody
SKU:CAB15820
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-296 of human MMADHC (NP_056517.1).
Sequence:MANV LCNR ARLV SYLP GFCS LVKR VVNP KAFS TAGS SGSD ESHV AAAP PDIC SRTV WPDE TMGP FGPQ DQRF QLPG NIGF DCHL NGTA SQKK SLVH KTLP DVLA EPLS SERH EFVM AQYV NEFQ GNDA PVEQ EINS AETY FESA RVEC AIQT CPEL LRKD FESL FPEV ANGK LMIL TVTQ KTKN DMTV WSEE VEIE REVL LEKF INGA KEIC YALR AEGY WADF IDPS SGLA FFGP YTNN TLFE TDER YRHL GFSV DDLG CCKV IRHS LWGT HVVV GSIF TNAT PDSH IMKK LSGN
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:cblD; C2orf25; CL25022; MMADHC
Positive Sample:293T,NIH/3T3,HeLa,MCF7
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Mitochondrion.
Calculated MW:33kDa
Observed MW:33kDa

This gene encodes a mitochondrial protein that is involved in an early step of vitamin B12 metabolism. Vitamin B12 (cobalamin) is essential for normal development and survival in humans. Mutations in this gene cause methylmalonic aciduria and homocystinuria type cblD (MMADHC), a disorder of cobalamin metabolism that is characterized by decreased levels of the coenzymes adenosylcobalamin and methylcobalamin. Pseudogenes have been identified on chromosomes 11 and X.

Purification Method:Affinity purification
Gene ID:27249
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using MMADHC Rabbit pAb (CAB15820) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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