The MLXIP Polyclonal Antibody (CAB17639) is a valuable tool for researchers studying MLXIP, a key transcriptional regulator involved in cellular metabolism and tumorigenesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the MLXIP protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for studies in cancer research and metabolic regulation.
MLXIP, also known as MAX-like protein X interacting protein, plays a crucial role in coordinating the expression of genes involved in glucose and lipid metabolism. Dysregulation of MLXIP has been implicated in various cancers, making it a promising target for therapeutic interventions. By investigating the function of MLXIP, researchers can gain valuable insights into the molecular mechanisms driving tumorigenesis and potentially identify new strategies for cancer treatment.
Product Name:
MLXIP Rabbit Polyclonal Antibody
SKU:
CAB17639
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human MLXIP (NP_055753.3).
Sequence:
ARAH ASAA PPPP RAGP GREE PPRR QQII HSGH FMVS SPHR EHPP KKGY DFDT VNKQ TCQT YSFG KTSS CHLS IDAS LTKL FECM TLAY SGKL VSPK WKNF K
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
MIR; MONDOA; bHLHe36; MLXIP
Positive Sample:
Rat lung
Conjugate:
Unconjugated
Cellular Localization:
mitochondrial outer membrane, nucleus
Calculated MW:
101kDa
Observed MW:
91kDa
This gene encodes a protein that functions as part of a heterodimer to activate transcription. The encoded protein forms a heterodimer with Max-like protein X (MLX) and is involved in the regulation of genes in response to cellular glucose levels.
Purification Method:
Affinity purification
Gene ID:
22877
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat lung, using MLXIP Rabbit pAb (CAB17639) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.