The MLST8 Polyclonal Antibody (CAB13599) is a valuable research tool for studying MLST8, a protein that plays a key role in the mTORC1 signaling pathway involved in cell growth and metabolism. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the MLST8 protein, researchers can analyze its expression and function in various cell types, making it ideal for studies in cell biology, metabolism, and cancer research.
MLST8, also known as GbL, is a crucial component of the mTORC1 complex, which regulates cell growth and metabolism in response to nutrient availability and growth factors. Dysregulation of this pathway has been implicated in diseases such as cancer, diabetes, and neurodegenerative disorders, making MLST8 a promising therapeutic target for drug development. Investigating the role of MLST8 can provide insights into cellular processes and potential treatment strategies for a variety of diseases.
Product Name:
MLST8 Rabbit Polyclonal Antibody
SKU:
CAB13599
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human MLST8 (NP_001186103.1).
Enables protein serine/threonine kinase activator activity. Involved in TORC1 signaling; positive regulation of TOR signaling; and regulation of actin cytoskeleton organization. Part of TORC1 complex and TORC2 complex.
Purification Method:
Affinity purification
Gene ID:
64223
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MLST8 Rabbit pAb (CAB13599) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
