The MLLT3 Polyclonal Antibody (CAB15690) is a key tool for researchers studying MLLT3, a protein involved in gene regulation and chromosomal translocations. This antibody, produced in rabbits, shows high specificity for human samples and is validated for use in Western blot applications. It binds specifically to the MLLT3 protein, enabling precise detection and analysis in various cell types, making it ideal for studies in oncology and hematological research.MLLT3, also known as AF9, is a crucial component of the MLL gene fusion complex, which is commonly found in leukemias and other hematological malignancies.
Understanding the function and regulation of MLLT3 is essential for unraveling the mechanisms of these diseases and developing targeted therapies. The MLLT3 Polyclonal Antibody opens up new possibilities for investigating the role of MLLT3 in cancer progression and treatment, paving the way for novel therapeutic strategies in the field of oncology.
Product Name:
MLLT3 Rabbit Polyclonal Antibody
SKU:
CAB15690
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human MLLT3/AF9 (NP_004520.2).
Enables chromatin binding activity and lysine-acetylated histone binding activity. Involved in several processes, including hematopoietic stem cell differentiation; positive regulation of transcription, DNA-templated; and regulation of stem cell division. Acts upstream of or within negative regulation of canonical Wnt signaling pathway and positive regulation of Wnt signaling pathway, planar cell polarity pathway. Located in cytosol and nucleoplasm. Part of transcription elongation factor complex.
Purification Method:
Affinity purification
Gene ID:
4300
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MLLT3/AF9 Rabbit pAb (CAB15690) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
