The MLLT10 Polyclonal Antibody (CAB14260) is a valuable tool for researchers studying the MLLT10 protein, which is involved in gene regulation and transcriptional activation in various cellular processes. This antibody, produced from rabbit serum, exhibits high reactivity towards human samples and has been validated for use in Western blot applications. By specifically binding to the MLLT10 protein, this antibody enables precise detection and analysis in different cell types, making it an ideal choice for studies focusing on gene expression and transcriptional regulation.
MLLT10, also known as ENL (eleven-nineteen leukemia), is a crucial component of the super elongation complex that regulates transcription elongation and chromatin modification. Dysregulation of MLLT10 has been linked to various types of leukemia and other cancers, highlighting its importance in cell growth and differentiation. The ability to study and manipulate MLLT10 function through this antibody can provide valuable insights into the molecular mechanisms underlying these diseases and potentially lead to the development of targeted therapies.
Product Name:
MLLT10 Rabbit Polyclonal Antibody
SKU:
CAB14260
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 250-500 of human MLLT10 (NP_001182555.1).
This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8028
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MLLT10 Rabbit pAb (CAB14260) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
