The MLLT1 Polyclonal Antibody (CAB18333) is a valuable tool for researchers studying MLLT1, a protein known to be involved in gene regulation and leukemia. This rabbit-derived antibody is highly specific to human MLLT1 and has been validated for use in Western blot applications. By binding to the MLLT1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and cancer research.MLLT1, also known as ENL or LTG19, is a fusion partner in several leukemia-associated chromosomal translocations and is thought to play a role in transcriptional regulation.
Understanding the function of MLLT1 is crucial for deciphering its involvement in leukemia development and progression. By utilizing the MLLT1 Polyclonal Antibody, researchers can gain insights into the mechanisms underlying MLLT1's influence on gene expression and potential therapeutic targets for leukemia treatment.
Product Name:
MLLT1 Rabbit Polyclonal Antibody
SKU:
CAB18333
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 190-270 of human MLLT1 (NP_005925.2).
cytosol, fibrillar center, nucleoplasm, transcription elongation factor complex
Calculated MW:
62kDa
Observed MW:
80kDa/62kDa
Predicted to be involved in regulation of transcription, DNA-templated. Predicted to act upstream of or within negative regulation of protein kinase activity. Located in cytosol; fibrillar center; and nucleoplasm. Part of transcription elongation factor complex.
Purification Method:
Affinity purification
Gene ID:
4298
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MLLT1 Rabbit pAb (CAB18333) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
