MLK4 Antibody (PACO01070)
- SKU:
- PACO01070
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
MLK4 Antibody (PACO01070)
The MLK4 Antibody (PACO01070) is a polyclonal antibody designed for research involving MLK4, a key protein kinase in various signaling pathways. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications.MLK4, also known as mixed lineage kinase 4, plays a crucial role in cell signaling and regulation, with implications in cancer progression, neurodegenerative diseases, and inflammatory responses. By targeting MLK4 with this antibody, researchers can accurately detect and analyze its expression in various cell types, providing valuable insights into its function and potential therapeutic targeting.
With its high specificity and reactivity in human samples, the MLK4 Antibody (PACO01070) is a valuable tool for researchers studying cell signaling pathways, cancer biology, and neurodegenerative disorders. Its use in Western blot applications allows for precise detection and analysis of MLK4 protein levels, aiding in the advancement of research towards developing targeted therapies and understanding disease mechanisms.
| Antibody Name: | MLK4 Antibody |
| Antibody SKU: | PACO01070 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the Internal region of human MLK4. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | MLK4; KIAA1804; Mitogen-activated protein kinase kinase kinase MLK4; Mixed lineage kinase 4 |
| UniProt Protein Function: | MLK4: Activates the JUN N-terminal pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Protein kinase, TKL; Kinase, protein; Motility/polarity/chemotaxis; EC 2.7.11.25; Protein kinase, Ser/Thr (non-receptor); TKL group; MLK family; MLK subfamily Chromosomal Location of Human Ortholog: 1q42 Molecular Function:protein binding; protein homodimerization activity Biological Process: activation of JNK activity; protein amino acid autophosphorylation; protein amino acid phosphorylation |
| UniProt Code: | Q5TCX8 |
| NCBI GenInfo Identifier: | 71153820 |
| NCBI Gene ID: | 84451 |
| NCBI Accession: | Q5TCX8.1 |
| UniProt Secondary Accession: | Q5TCX8,Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1, B2RN34 |
| UniProt Related Accession: | Q5TCX8 |
| Molecular Weight: | 52,817 Da |
| NCBI Full Name: | Mitogen-activated protein kinase kinase kinase MLK4 |
| NCBI Official Symbol: | KIAA1804Â Â |
| NCBI Official Synonym Symbols: | MLK4; dJ862P8.3Â Â |
| NCBI Protein Information: | mitogen-activated protein kinase kinase kinase MLK4 |
| UniProt Protein Name: | Mitogen-activated protein kinase kinase kinase MLK4 |
| UniProt Synonym Protein Names: | Mixed lineage kinase 4 |
| Protein Family: | Mitogen-activated protein kinase kinase kinase |
| UniProt Gene Name: | MLK4Â Â |
| UniProt Entry Name: | M3KL4_HUMAN |
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