The MLF1 Polyclonal Antibody (CAB8012) is specifically designed for research involving the MLF1 protein, which is known to play a key role in cellular processes such as regulation of gene expression and cell differentiation. Raised in rabbits, this antibody is highly reactive with human samples and is validated for use in Western blot applications. By binding to the MLF1 protein, it enables researchers to detect and analyze this important molecule in various cell types, making it an ideal tool for studies in molecular biology and cancer research.
MLF1, also known as myelodysplasia/myeloid leukemia factor 1, is associated with leukemia and other hematological disorders, making it a critical target for investigation. Understanding the function and regulation of MLF1 is vital for unraveling its role in disease development and progression, and for identifying potential therapeutic targets. The MLF1 Polyclonal Antibody offers a valuable tool for researchers seeking to delve deeper into the mechanisms underlying these conditions and to develop novel approaches for their treatment.
Product Name:
MLF1 Rabbit Polyclonal Antibody
SKU:
CAB8012
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-268 of human MLF1 (NP_071888.1).
This gene encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Translocations between this gene and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4291
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MLF1 antibody (CAB8012) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
