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MLC1 Rabbit Polyclonal Antibody (CAB12840)

SKU:
CAB12840
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
€139 - €419
Frequently bought together:

Description

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MLC1 Rabbit Polyclonal Antibody (CAB12840)

The MLC1 Polyclonal Antibody (CAB12840) is a highly specific and sensitive tool for investigating the protein MLC1, which is associated with megalencephalic leukoencephalopathy with subcortical cysts (MLC), a rare genetic disorder affecting the brain. This antibody, raised in rabbits, is validated for use in various applications, including Western blot and immunofluorescence, enabling researchers to study the expression and localization of MLC1 in different cell types and tissues.MLC1 is a transmembrane protein primarily expressed in astrocytes and oligodendrocytes in the brain, where it plays a crucial role in maintaining ion and water homeostasis in the central nervous system.

Mutations in the MLC1 gene lead to dysregulation of these processes, resulting in the characteristic white matter abnormalities seen in MLC patients.By using the MLC1 Polyclonal Antibody, researchers can further explore the function and regulation of MLC1 in normal brain development and function, as well as in the pathogenesis of MLC. This antibody is a valuable tool for studying the molecular mechanisms underlying MLC and developing potential therapeutic strategies for this devastating neurological disorder.