The MLANA Polyclonal Antibody (CAB6290) is a valuable tool for researchers studying MLANA, a melanoma-associated antigen. This antibody, produced in rabbits, is highly specific in recognizing MLANA in human samples and is validated for use in Western blot applications. By binding to the MLANA protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for investigations in cancer research and immunotherapy.MLANA, also known as Melan-A, is a marker expressed by melanocytes and melanoma cells, playing a crucial role in melanocyte differentiation and melanoma progression.
Its significance in melanoma research makes it a valuable target for understanding the pathogenesis and potential therapeutic targets in melanoma. The MLANA Polyclonal Antibody is a valuable tool for researchers seeking to unravel the complexities of melanoma biology and develop novel approaches for diagnosis and treatment.
Product Name:
MLANA Rabbit Polyclonal Antibody
SKU:
CAB6290
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 48-118 of human Melan-A/MART-1 (NP_005502.1).
Endoplasmic reticulum membrane, Golgi apparatus, Melanosome, Single-pass type III membrane protein, trans-Golgi network membrane.
Calculated MW:
13kDa
Observed MW:
19kDa
Located in endoplasmic reticulum membrane; melanosome; and trans-Golgi network.
Purification Method:
Affinity purification
Gene ID:
2315
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Melan-A/MART-1 Rabbit pAb antibody (CAB6290) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
