null

MKP1 Polyclonal Antibody (CAB24667)

SKU:
CAB24667
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€129 - €359
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:MKP1 Polyclonal Antibody
SKU:CAB24667
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 267-367 of human MKP1 (NP_004408.1).
Sequence:TICL AYLM RTNR VKLD EAFE FVKQ RRSI ISPN FSFM GQLL QFES QVLA PHCS AEAG SPAM AVLD RGTS TTTV FNFP VSIP VHST NSAL SYLQ SPIT TSPS C
Tested Applications:WB ELISA
Recommended Dilution:WB,1:100 - 1:500
Synonyms:HVH1; MKP1; CL100; MKP-1; PTPN10
Positive Sample:HeLa
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:39kDa
Observed MW:40kDa

The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy.

Purification Method:Affinity purification
Gene ID:1843
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using MKP1 Rabbit pAb (CAB24667) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Negative control (NC):THP-1Exposure time: 3s.

Related Products