The MKNK1 Polyclonal Antibody (CAB18429) is a valuable tool for researchers studying MKNK1, a protein involved in the regulation of cell growth and proliferation. This rabbit polyclonal antibody is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the MKNK1 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for studies in cell signaling, cancer biology, and drug development.MKNK1 is a key player in the MAP kinase signaling pathway, which is known to regulate important cellular processes such as cell differentiation, proliferation, and survival.
Dysregulation of MKNK1 has been implicated in various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions. Therefore, understanding the function and regulation of MKNK1 is essential for developing targeted therapies and diagnostic tools for these diseases.Overall, the MKNK1 Polyclonal Antibody (CAB18429) is a reliable reagent that can help advance research in the fields of cell signaling, cancer biology, and drug discovery. Its high specificity and sensitivity make it a valuable asset for scientists studying MKNK1 and its role in various physiological and pathological processes.
Product Name:
MKNK1 Rabbit Polyclonal Antibody
SKU:
CAB18429
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 374-465 of human MKNK1 (NP_003675.2).
This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene.
Purification Method:
Affinity purification
Gene ID:
8569
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MKNK1 Rabbit pAb (CAB18429) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
