The MKL2 Polyclonal Antibody (CAB13113) is a valuable tool for researchers studying the MKL2 protein, a key regulator of gene expression involved in various cellular processes. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot experiments. By binding to the MKL2 protein, this antibody enables precise detection and analysis in a wide range of cell types, making it an ideal choice for studies in molecular biology and cancer research.MKL2, also known as MRTF-A, is a transcriptional coactivator that plays a crucial role in the regulation of gene expression in response to various stimuli, such as mechanical stress and growth factors.
Its involvement in processes like cell migration, proliferation, and differentiation makes it a promising target for investigation in diseases such as cancer and cardiovascular disorders. Understanding the function of MKL2 is essential for uncovering its potential therapeutic applications in these pathological conditions.
Product Name:
MKL2 Rabbit Polyclonal Antibody
SKU:
CAB13113
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 170-300 of human MKL2 (NP_054767.3).
Enables transcription coactivator activity. Involved in positive regulation of pri-miRNA transcription by RNA polymerase II and positive regulation of striated muscle tissue development. Predicted to be located in cytoplasm. Predicted to be active in nucleus.
Purification Method:
Affinity purification
Gene ID:
57496
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MKL2 Rabbit pAb (CAB13113) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
