MKKS Rabbit Polyclonal Antibody (CAB15336)
- SKU:
- CAB15336
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | MKKS Rabbit Polyclonal Antibody |
SKU: | CAB15336 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 221-570 of human MKKS (NP_740754.1). |
Sequence: | EMSE VQLM RLLP IKKS TALK VALF CTTL SGDT SDTG EGTV VVSY GVSL ENAV LDQL LNLG RQLI SDHV DLVL CQKV IHPS LKQF LNMH RIIA IDRI GVTL MEPL TKMT GTQP IGSL GSIC PNSY GSVK DVCT AKFG SKHF FHLI PNEA TICS LLLC NRND TAWD ELKL TCQT ALHV LQLT LKEP WALL GGGC TETH LAAY IRHK THND PESI LKDD ECTQ TELQ LIAE AFCS ALES VVGS LEHD GGEI LTDM KYGH LWSV QADS PCVA NWPD LLSQ CGCG LYNS QEEL NWSF LRST RRPF VPQS CLPH EAVG SASN LTLD CLTA KLSG LQVA VETA NLIL DLSY VIED KN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | KMS; MKS; BBS6; HMCS; MKKS |
Positive Sample: | K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, centrosome, cytoskeleton, cytosol, microtubule organizing center. |
Calculated MW: | 62kDa |
Observed MW: | 62kDa |
This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6, also known as McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 8195 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |