The MKI67 Polyclonal Antibody (CAB11390) is a crucial tool for researchers studying the MKI67 protein, also known as Ki-67, which is a marker of cellular proliferation and is commonly used in cancer research. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.The MKI67 Polyclonal Antibody binds specifically to the MKI67 protein, allowing for accurate detection and analysis in a variety of cell types. Its use is particularly beneficial in studies of cell proliferation, cell cycle regulation, and tumor growth, making it an essential tool for researchers in the fields of oncology, cell biology, and molecular biology.
Given the important role of MKI67 in cancer development and progression, this antibody is a valuable asset for investigating potential biomarkers and therapeutic targets for various types of cancer. Its reliable performance and specificity make it an ideal choice for researchers seeking to unravel the complexities of cellular proliferation and its implications in disease.
Product Name:
Ki67 Rabbit Polyclonal Antibody
SKU:
CAB11390
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 700-800 of human Ki67 (NP_002408.3).
Enables protein C-terminus binding activity. Involved in regulation of chromosome segregation and regulation of mitotic nuclear division. Located in chromosome; nuclear body; and nucleolus. Colocalizes with condensed chromosome. Implicated in Crohn's disease; breast cancer; human immunodeficiency virus infectious disease; and pancreatic cancer. Biomarker of several diseases, including Barrett's esophagus; autoimmune disease of musculoskeletal system (multiple); endocrine gland cancer (multiple); gastrointestinal system cancer (multiple); and interstitial cystitis.
Purification Method:
Affinity purification
Gene ID:
4288
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunofluorescence analysis of HeLa cells using Ki67 Rabbit pAb (CAB11390) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
