The Mixl1 Polyclonal Antibody (CAB17223) is a valuable tool for researchers studying Mixl1, a transcription factor essential for the development of hematopoietic stem cells and cardiac mesoderm. This antibody, produced in rabbits, exhibits high reactivity with human and mouse samples, making it suitable for a wide range of research applications.Mixl1 is a key player in early embryonic development, particularly in the formation of blood and heart tissues. Dysregulation of Mixl1 expression has been implicated in various developmental disorders and diseases, making it an important target for investigation in the fields of stem cell biology and cardiovascular research.
This antibody specifically binds to Mixl1 protein, enabling researchers to detect and analyze its expression in various cell types and tissues. Its validation for use in techniques such as Western blotting and immunohistochemistry ensures reliable and accurate results in experiments aimed at understanding the role of Mixl1 in development and disease. By elucidating the function of Mixl1, researchers can gain insights that may lead to the development of novel therapies for conditions related to hematopoiesis and cardiogenesis.
Product Name:
MIXL1 Rabbit Polyclonal Antibody
SKU:
CAB17223
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-232 of human MIXL1 (NP_114150.1).
Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and sequence-specific double-stranded DNA binding activity. Predicted to be involved in several processes, including endodermal cell differentiation; hematopoietic progenitor cell differentiation; and positive regulation of mesoderm development. Predicted to act upstream of or within cell migration involved in gastrulation and hemopoiesis. Located in nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
83881
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MIXL1 Rabbit pAb (CAB17223) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5min.
