The Mitofusin-1 Polyclonal Antibody (CAB9880) is a valuable tool for researchers studying mitochondrial dynamics and function. Mitofusin-1 is a protein involved in mitochondrial fusion, a process essential for maintaining mitochondrial health and proper cellular function. This antibody, generated in rabbits, specifically recognizes Mitofusin-1 in human samples and is validated for use in Western blot applications.By targeting Mitofusin-1, researchers can investigate the role of mitochondrial fusion in various cellular processes, including energy production, apoptosis regulation, and cellular signaling. Dysregulation of mitochondrial dynamics has been linked to a range of human diseases, making Mitofusin-1 an important target for studies in areas such as neurodegeneration, metabolic disorders, and cancer.
The Mitofusin-1 Polyclonal Antibody enables precise detection and analysis of Mitofusin-1 protein levels in different cell types, providing essential information for understanding the mechanisms underlying mitochondrial dynamics and their impact on cellular physiology. This antibody is a valuable tool for researchers interested in exploring the intricate relationship between mitochondrial function and disease pathology.
Product Name:
MFN1 Rabbit Polyclonal Antibody
SKU:
CAB9880
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 622-741 of human Mitofusin-1/MFN1 (NP_284941.2).
The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.
Purification Method:
Affinity purification
Gene ID:
55669
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Mitofusin-1/MFN1 Rabbit pAb (CAB9880) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
