MITF Rabbit Polyclonal Antibody (CAB1255)
- SKU:
- CAB1255
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | MITF Rabbit Polyclonal Antibody |
SKU: | CAB1255 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human MITF (NP_937801.1). |
Sequence: | MLEM LEYN HYQV QTHL ENPT KYHI QQAQ RQQV KQYL STTL ANKH ANQV LSLP CPNQ PGDH VMPP VPGS SAPN SPMA MLTL NSNC EKEG FYKF EEQN RAES ECPG MNTH SRAS CMQM DDVI DDII SLES SYNE EILG LMDP ALQM ANTL PVSG NLID LYGN QGLP PPGL TISN SCPA NLPN IKRE LTES EARA LAKE RQKK DNHN LIER RRRF NIND RIKE LGTL IPKS NDPD MRWN KGTI LKAS VDYI RKLQ REQQ RAKE LENR QKKL EHAN RHLL LRIQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | MI; WS2; CMM8; WS2A; COMMAD; MITF-A; bHLHe32; MITF |
Positive Sample: | Jurkat,K-562,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 59kDa |
Observed MW: | 50-70kDa |
The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome.
Purification Method: | Affinity purification |
Gene ID: | 4286 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |