The MITD1 Polyclonal Antibody (CAB18540) is a valuable tool for researchers studying MITD1, a protein involved in various cellular processes, including cell division, DNA repair, and apoptosis. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the MITD1 protein, researchers can accurately detect and analyze MITD1 expression in a variety of cell types, making it an essential reagent for studies in cell biology and cancer research.
MITD1 is a multifunctional protein that plays a crucial role in maintaining genomic stability and regulating cell growth and survival. Its involvement in key cellular functions makes it a promising target for investigating diseases such as cancer, where dysregulation of MITD1 can lead to uncontrolled cell proliferation and tumor progression. By understanding the role of MITD1 in these processes, researchers can develop novel strategies for diagnosing and treating cancer and other related disorders.
Product Name:
MITD1 Rabbit Polyclonal Antibody
SKU:
CAB18540
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-249 of human MITD1 (NP_620153.1).
Abscission, the separation of daughter cells at the end of cytokinesis, is effected by endosomal sorting complexes required for transport III (ESCRT-III). The protein encoded by this gene functions as a homodimer, with the N-termini binding to a subset of ESCRT-III subunits and the C-termini binding to membranes. The encoded protein regulates ESCRT-III activity and is required for proper cytokinesis. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
129531
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MITD1 Rabbit pAb (CAB18540) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
