The MIS12 Polyclonal Antibody (CAB15508) is specially developed for research involving the MIS12 protein, a key component of the Mis12 complex that plays a crucial role in chromosome segregation during cell division. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications such as Western blot and immunofluorescence.The MIS12 protein is essential for ensuring accurate chromosome segregation and proper cell division, making it a critical target for studies in cell biology, genetics, and cancer research. By detecting and analyzing the MIS12 protein in different cell types, researchers can gain insights into the mechanisms underlying cell division and potential implications for diseases such as cancer.
The MIS12 Polyclonal Antibody enables accurate detection and analysis of the MIS12 protein, allowing researchers to further understand its functions and potential therapeutic implications in conditions related to cell division and chromosome segregation. Its versatility and high reactivity make it an invaluable tool for advancing research in the fields of cell biology and cancer biology.
Product Name:
MIS12 Rabbit Polyclonal Antibody
SKU:
CAB15508
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human MIS12 (NP_076944.1).
Involved in attachment of mitotic spindle microtubules to kinetochore and kinetochore assembly. Located in kinetochore and nucleus. Part of MIS12/MIND type complex.
Purification Method:
Affinity purification
Gene ID:
79003
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MIS12 Rabbit pAb (CAB15508) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
