The MIPEP Polyclonal Antibody (CAB12640) is specially developed for researchers studying MIPEP, a mitochondrially localized enzyme involved in peptide processing. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the MIPEP protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal tool for investigations in mitochondrial biology and related fields.MIPEP, also known as mitochondrial intermediate peptidase, plays a crucial role in the processing of mitochondrial targeting sequences and other precursor proteins within the mitochondria.
Dysfunction of MIPEP has been linked to a range of mitochondrial disorders and diseases, highlighting the importance of studying its role in cellular metabolism and protein processing. By understanding the function of MIPEP, researchers can gain insights into mitochondrial function and potential therapeutic targets for mitochondrial-related disorders.
Product Name:
MIPEP Rabbit Polyclonal Antibody
SKU:
CAB12640
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 511-713 of human MIPEP (NP_005923.2).
The product of this gene performs the final step in processing a specific class of nuclear-encoded proteins targeted to the mitochondrial matrix or inner membrane. This protein is primarily involved in the maturation of oxidative phosphorylation (OXPHOS)-related proteins. This gene may contribute to the functional effects of frataxin deficiency and the clinical manifestations of Friedreich ataxia.
Purification Method:
Affinity purification
Gene ID:
4285
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MIPEP Rabbit pAb (CAB12640) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
