The MIP Polyclonal Antibody (CAB2886) is a valuable tool for researchers studying the MIP protein, a cytokine involved in immune responses, inflammation, and tumor progression. This antibody, generated in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the MIP protein, this antibody allows for precise detection and analysis in various cell types, making it an excellent choice for studies in immunology, cancer research, and inflammatory diseases.
MIP, also known as macrophage inflammatory protein, is a key player in the regulation of inflammatory responses and the recruitment of immune cells to sites of infection or injury. Its role in promoting tumor growth and metastasis makes it a potential target for therapeutic intervention in cancer. Understanding the mechanisms by which MIP influences immune function and tumor development is essential for the development of effective treatments for cancer and other inflammatory conditions.
Product Name:
MIP Rabbit Polyclonal Antibody
SKU:
CAB2886
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human MIP (NP_036196.1).
Cell junction, Cell membrane, Multi-pass membrane protein, gap junction.
Calculated MW:
28kDa
Observed MW:
28kDa
Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in a potential gene cluster at 12q13.
Purification Method:
Affinity purification
Gene ID:
4284
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using MIP Rabbit pAb (CAB2886) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
