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MIP 1a Monoclonal Antibody [YNR-HMIP1a] (CPAB0001)

SKU:
CPAB0001
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
YNR-HMIP1a
Applications:
IP
WB
ELISA
€660
Frequently bought together:

Description

system_update_alt Datasheet

MIP 1a Monoclonal Antibody [YNR-HMIP1a] (CPAB0001)

The MIP-1a Polyclonal Antibody (CPAB0001) is a valuable tool for researchers studying the chemokine MIP-1a, an important signaling molecule involved in immune responses and inflammation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is specifically validated for use in Western blot applications. By binding to the MIP-1a protein, this antibody enables precise detection and analysis in various cell types, making it an ideal choice for studies in immunology, inflammation, and infectious diseases.

MIP-1a, also known as macrophage inflammatory protein 1 alpha, is a key player in orchestrating immune cell recruitment and activation in response to infection or tissue damage. Its involvement in inflammatory processes and immune cell communication highlights its potential as a therapeutic target for conditions like arthritis, psoriasis, and HIV/AIDS. Investigating the role of MIP-1a using this antibody can provide valuable insights into the underlying mechanisms of these diseases and aid in the development of targeted treatments.

Product Name:MIP 1a Antibody
Product Sku:CPAB0001
Size:500μg
Host Species:Mouse
Immunogen:r.Human MIP1-a
Clone:YNR-HMIP1a.
Reactivity:Human
Applications:Immuneprecipitation, Western Blot, ELISA
Purification Method:Ion exchange
Isotype:IgG1
Background:Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP-1a and MIP-1b that are now officially named CCL3 and CCL4 respectively. Both are major factors produced by macrophages after they are stimulated with bacterial endotoxins. They activate human granulocytes (neutrophils, eosinophilsand basophils) which can lead to acute neutrophilic inflammation. They also induce the synthesis and release of other pro-inflammatory cytokines such as interleukin 1(IL-1), IL-6 and TNF-a from fibroblasts and macrophages. The genes for CCL3 and CCL4 are both located on human chromosome 17.
Synonyms:Worked Small inducible cytokine A3, CCL3, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, Tonsillar lymphocyte LD78 alpha protein, G0/G1 switch regulatory protein 19-1, G0S19-1 protein, SIS-beta, PAT 464.1, chemokine (C-C motif) ligand 3, MIP1A, SCYA3, G0S19-1, LD78ALPHA.
Storage Buffer:In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

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