The Mios Polyclonal Antibody (CAB18260) is a valuable tool for researchers studying the Mios protein, a key player in cell division and chromosome segregation processes. This antibody, created in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the Mios protein, this antibody facilitates the detection and analysis of Mios in a variety of cell types, making it ideal for investigations in cell biology and cancer research.Mios, also known as CCDC135, is essential for ensuring accurate chromosome segregation during cell division, making it a crucial target for studying cell cycle regulation and genomic stability.
Dysfunction of Mios has been linked to chromosomal instability and cancer development, highlighting the importance of understanding its role in cellular processes. By using the Mios Polyclonal Antibody, researchers can gain insights into the functions of Mios and its implications in various diseases, paving the way for potential therapeutic interventions targeting this protein.
Product Name:
MIOS Rabbit Polyclonal Antibody
SKU:
CAB18260
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 556-875 of human MIOS (NP_061878.3).
Involved in cellular response to amino acid starvation; positive regulation of TOR signaling; and protein-containing complex localization. Located in several cellular components, including cytosol; lysosomal membrane; and nucleoplasm. Part of GATOR2 complex.
Purification Method:
Affinity purification
Gene ID:
54468
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MIOS Rabbit pAb (CAB18260) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
