The MINPP1 Polyclonal Antibody (PAC02846) is a valuable tool for researchers studying the MINPP1 protein, an important enzyme involved in cellular metabolism and signaling pathways. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the MINPP1 protein, this antibody allows for the detection and analysis of MINPP1 in a variety of cell types, making it ideal for studies in cell biology, metabolism, and cancer research.MINPP1, also known as multiple inositol polyphosphate phosphatase 1, plays a critical role in regulating inositol signaling and phosphate metabolism in cells.
Dysregulation of MINPP1 has been implicated in various diseases, including cancer, metabolic disorders, and neurodegenerative conditions. Understanding the function and regulation of MINPP1 is essential for developing targeted therapies and interventions for these diseases.Overall, the MINPP1 Polyclonal Antibody is a powerful tool for researchers seeking to investigate the role of the MINPP1 protein in cellular processes and disease pathology. Its high specificity and sensitivity make it an invaluable resource for advancing our understanding of MINPP1 and its potential as a therapeutic target.
Antibody Name:
Minpp1 Antibody (PACO28246)
Antibody SKU:
PACO28246
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Rat
Immunogen:
Recombinant Rat Multiple inositol polyphosphate phosphatase 1 protein (31-481AA)
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification).
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy ().
UniProt Protein Details:
NCBI Summary:
catalyzes the hydrolysis of Ins(1,3,4,5,6)P5, first to Ins(1,4,5,6)P4 and then to Ins(1,4,5)P3, by consecutive 3- and 6-phosphatase activities [RGD, Feb 2006]
