The Mimecan Polyclonal Antibody (CAB6679) is a valuable tool for researchers studying Mimecan, a cell surface proteoglycan involved in various biological processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to Mimecan protein, this antibody enables accurate detection and analysis in a wide range of cell types, making it ideal for investigations in the fields of cell biology, development, and tissue regeneration.Mimecan, also known as OGN (Osteoglycin), is a multifunctional protein that plays a crucial role in regulating collagen fibrillogenesis, cell adhesion, and tissue remodeling.
Its involvement in these processes makes Mimecan a key player in bone development, cartilage formation, and wound healing. Furthermore, dysregulation of Mimecan expression has been linked to various diseases, including osteoarthritis, cancer, and cardiovascular disorders. By studying Mimecan with the CAB6679 antibody, researchers can gain insights into its function and potential therapeutic targets for related conditions.
Product Name:
OGN Rabbit Polyclonal Antibody
SKU:
CAB6679
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-298 of human Osteoglycin (OGN) (NP_054776.1).
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4969
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Osteoglycin (OGN) Rabbit pAb (CAB6679) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
