The MILR1 Antibody (PACO46742) is a polyclonal antibody designed for research involving MILR1, a cell surface molecule implicated in immune regulation. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications including Western blot analysis. By binding to the MILR1 protein, this antibody enables the detection and analysis of MILR1 in different cell types, making it a valuable tool for studies in immunology and cancer research.MILR1, also known as immune inhibitory receptor 1, plays a crucial role in immune homeostasis by regulating immune responses and inhibiting inflammatory reactions.
Its importance in immune system modulation makes it a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the role of MILR1 is essential for developing therapies that can manipulate immune function in these disease contexts.Overall, the MILR1 Antibody (PACO46742) is a reliable tool for researchers interested in studying MILR1 and its impact on immune regulation and disease pathology. Its specificity and reactivity with human samples make it a valuable asset for a wide range of research applications.
Western blot. All lanes: MILR1 antibody at 14 µg/ml. Lane 1: Mouse brain tissue. Lane 2: HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 39, 28, 29 kDa. Observed band size: 39, 120 kDa..
Immunofluorescent analysis of HepG2 cells using PACO46742 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human liver cancer using PACO46742 at dilution of 1:100.
Background:
Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction (By similarity).
MCA32: Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE- mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 17q23.3Biological Process: mast cell degranulation; negative regulation of mast cell activation
