The MIF Polyclonal Antibody is a vital tool for researchers studying the Macrophage Migration Inhibitory Factor (MIF), a key cytokine involved in immune responses and inflammation. This antibody, generated in rabbits, exhibits high specificity for MIF and has been extensively validated for Western blotting applications with human samples. By targeting MIF, researchers can analyze its expression levels and investigate its role in various cellular processes, providing valuable insights into conditions like cancer, autoimmune diseases, and inflammatory disorders.
MIF, a pro-inflammatory cytokine, has been implicated in numerous pathologies, including cancer, rheumatoid arthritis, and sepsis. Its ability to regulate immune responses and inflammatory pathways makes it a promising therapeutic target for drug development. The MIF Polyclonal Antibody enables researchers to delve deeper into the mechanisms underlying MIF's actions, paving the way for the development of novel therapies that modulate immune function and mitigate inflammatory diseases.
Product Name:
MIF Polyclonal Antibody
SKU:
CAB22014
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2-115 of human MIF (NP_002406.1).
This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.
Purification Method:
Affinity purification
Gene ID:
4282
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using [KO Validated] MIF Rabbit pAb (CAB22014) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
